It is nothing but an oversimplification of a complex problem. Very Good Summary, http://www.ironmagazineforums.com/history/topic/23051-1.html FEBS letters, 569(1-3), pp.169-172. With this form of treatment, another striking feature is the size of the facial skin pore. I myself have used the program and can report that it works quite well. 300mg for me is equivalent to about 6grams of B5. I don't know who made the false claims that pantithine is stronger then panothenic acid. Comparison of oral treatment with zinc sulfate and placebo in acne vulgaris. The US recommended dietary allowance (RDA) for pantothenic acid in nutritional supplements and foods is age dependent and ranges from 0.2 mg/kg in infants to 5 mg in adults. Irregular menstrual cycles and absent menses is common among lupus patients. Using this method, 12 SLE females were studied with promising results. (to be fair I've always been on BP, for the last 15 yrs and it's always helped my face, but I've never been clear always about 3 or more spots in one day. ACTH is secreted by the pituitary to stimulate more adrenal hormone synthesis. ------------------ Food Almost all plant- and animal-based foods contain pantothenic acid in varying amounts. adding that and zinc into my routine definitely helped me to control the problem. CoA is used at the cellular level for fatty acid oxidation and in many other biochemical reactions in the cell. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. The study talked about how Dr. Lit-Hung Leung (the doctor responsible for the study) had given the participants 10 grams of Pantothenic Acid (Vitamin B5) every day in 4 divided doses. My nose isn't shiny after all day at work. Just read the reviews, and you will see that not all brands of Pantothenic Acid are the same. The RDA during pregnancy and lactation is slightly higher, at 6 and 7 mg daily, respectively. However, despite one promising, yet relatively unsupported study, and anecdotal evidence, we are not recommending long-term supplementation of B5. http://lpi.oregonstate.edu/infocenter/vitamins/pa/ I hope others have the good fortune to find this product too. It has been shown to quite significantly reduce acne after 10 to 12 weeks of treatment. Cochrane T, Leslie G. The treatment of lupus erythematosus with calcium pantothenate and panthenol. This is so much better than trying to swallow 6-7 1G giant B5 pills. So for those with short attention span here are the keypoints: 1. Jul 16 2007, 12:44 PM After reading about pantethine (the active form of B-5), i'm wondering why people aren't trying it instead of b5? The vital organs are only involved much later on. Very well organized testimonials area with photos STUDY Pantothenic Acid (b5) and Acne Study by Dr Leung I take 300 mg of Pantethine, 3 times a day, so 900mg total. Site also contains info about b5 Common sources of pantothenic acid include liver, queen bee jelly, yeast, rice bran, molasses, peanuts, tree nuts, whole grains, mushrooms, eggs, milk, and potatoes. However, much can be done to improve quality of life of the lupus patient. Although no significant side effects occurred, the long-term safety of such large amounts taken orally has not been studied. Women with premenstrual acne may find benefit with vitamin B6. Previous Articles on Adrenal and B5: So, for the last 4 months I've seen nearly every kind of doctor in Washington; I've seen Naturopaths, visited Tacoma General Hospital for a Western Medicine practitioners diagnosis, I've been put on Accutane, and its been like a guessing game for them all. A total of 67 patients was treated, for periods of up http://orthomolecular.org/library/jom/1997/articles/1997-v12n02-p099.shtml I started taking B5 in january of 2001 and quit later in 2002. or if you never used b5 but are having success with pantethine please share. Many of the steroidal hormones are made by the adrenal gland, so it is very logical that B5 deficiency can result in a syndromes called adrenal failure, or the inability to synthesis steroidal hormones such as Cortisol. Dexpanthenol, considered a provitamin form, is the corresponding alcohol of pantothenic acid. The age ranged from 10 to 30, and with about 80% between 13 and 23. For more information on the use of B5, Pantothenic Acid and Adrenal Fatigue, see my previous article: Adrenal Fatigue by Jeffrey Dach MD FEBS letters, 569(1-3), pp.169-172. Section 107, the material on this site is distributed without profit to those who have an interest in using the included information for research and educational purposes. http://www.mitamins.com/library/Concern/Lupus.html. In high doses, pantothenic acid may inhibit the absorption of biotin produced by the microflora in the large intestine. This hypothesis is used to explain the high incidence of SLE in females, the role of sex hormones in this disease and the mechanism underlying a flare. It works the same as megadosing on B5. Welsh AL. PlEASE #SUBSCRIBE# so that I can grow and help others. http://www.coenzyme-a.com/acne_vulgaris.html John D. McCarthy, Norfolk, Virginia . Traditionally, acne is treated by the dermatologist with various topical cleansers, antibiotics and drugs such as Accutane. Also contains email correspondence with Dr Leung, Here is a brief summary of my own B5 use: by William G. Gray, • Started November 10th at 5 grams per day, • After noticeable acne clearing, increased dosage after 1 week to 10 grams per day, • After another 2 weeks of more dramatic improvements, increased dosage to 15 grams per day, and maintained daily dosage to present. No side effects of the therapy. I wish I had seen the info on pantethine before starting b5 powder 10 days ago. I found that many, but not all, of these acne sufferers had success with vitamin B5 (Pantethine) which did work for many of them. Like I said, my skin became much drier. I now only wish I had discovered B5 and pantethine earlier in my life like when I was in high school. This is only a brief summary of general information about this product. Sign up now. It is the active ingredient in Vitamin B5. I've found the B5 seems more effective if I don't take it with food, but rather take it at least 10-15 minutes before a meal or at least an hour afterward. Pantothenic acid is a vitamin, also known as vitamin B5, used as a dietary supplement when taken in recommended daily allowances (RDAs), and also to treat pantothenic acid deficiency. Pantothenic acid is found in all animal and plant tissues. Oral vitamin A in acne vulgaris. For example, a 12-week study in 41 adults with mild to moderate acne observed a significant reduction in inflamed lesions in those who consumed a pantothenic-acid-based … Now when i feel my face it feels smooth and im LOVING it, only continue'ing to get better too  im still getting 1 major pimple each week but thety get owned QUICK LOL so yea, IM A BELIEVER, PATETHINE = OWNAGE gonna post my next update sometime in a few more weeks  I hope it keeps working gonna alsp try some acv for my red spots see how that goes ... PEOPLE USE PANTETHINE FREAK B5, http://www.coenzyme-a.com/testimonial.html, Dear Coenzyme-A Technologies, For example, deficiency states such as beri beri and scurvy initially spare the vital organs, and  involve the skin and musculoskeletal system. J Am Acad Dermatol 1987;17:1033–41. Pantothenic acid is generally used in combination with various other B vitamin complexes like Vitamin B3, Vitamin B5, Vitamin B6, Vitamin B12, and folic acid. Consult with your doctor to get the required amount of Vitamin B5 dosage that is suitable for your body. Symptoms of transient nausea and gastric distress were reported as the only side effects of the therapy. The only negative side effects I noticed were minor diarrhea at first, accompanied by hunger cravings, both of which disappeared after a few days (the diarrhea after about 2). In some of these cases, in order to get a more immediate response, it may even be necessary to step up the dose to 15-20 grams a day. Carnitine transports long-chain acyl groups from fatty acids (Acyl group) into the mitochondrial matrix, so that they can be broken down through ß-oxidation to acetate to obtain usable energy via the citric acid cycle.
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